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Biopharmaceutical facility wins 2014 ISPE ‘Facility of the Year Award for Process Innovation’

We were engaged to provide the full range of design services (architectural fit-out, full engineering design and contract administration) for the new mammalian cell culture manufacturing facility. The six storey facility, operated by Patheon Biologics, forms part of a major research and biotechnology development located on the Princess Alexandra Hospital / University of Queensland campus in Brisbane and includes ISO5 to ISO8 cleanrooms, QC laboratories, offices and support spaces.

The world-class manufacturing facility was designed to high quality Good Manufacturing Practice (GMP) cleanroom requirements, including compliance to Australian, US and European regulations. The facility was recently awarded the 2014 ISPE Facility of the Year Award for Process Innovation.

"Amec Foster Wheeler played a critical role in BPA's on-time and on-budget delivery of the new $65M biologics manufacturing facility in Brisbane. They performed the entire interior fit-out design process, from concept development to a fully detailed package for tendering. They demonstrated great flexibility in a multi stakeholder project environment in order to integrate the state-of-the-art cGMP compliant design into the total project scope. During the construction phase, their inputs were essential in assuring the builder delivered outcomes consistent with the client's expectations. Great job.”
David Hughes, Chief Executive Officer, BioPharmaceuticals Australia

Highlights of the project included:

  • The manufacturing process is based on class leading single use technology, particularly the bioreactors but also the process preparation and purification steps. This technology ensures that the batch to batch turnaround is minimised and reduces the overall manufacturing facility footprint for an equivalent product output. It also assists the green credentials of the facility through significant reduction in cleaning requirements, hence reducing associated energy and infrastructure costs;
  • Complex HVAC ductwork and process services piping (WFI, purified water, clean steam) was modelled in 3D to assist in design detailing, services clash detection, services coordination and project visualisation.
Location:Brisbane, Australia
Client:BioPharmaceuticals Australia (BPA) / Patheon Biologics
Value:AUD$65 million
Scope:Architectural fit-out design, mechanical, electrical and process engineering, automation and controls, structural, hydraulic services, fire suppression, construction and commissioning assistance, validation
Date:2010 - 2013